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QDSTTM, rapid tuberculosis Drug Susceptibility Test

QDST is a rapid, phenotypic drug susceptibility testing system for tuberculosis. The system provides susceptibility test results for 13 drugs, including first and second line agents, in just a week, which can allow laboratories to shorten turnaround time by 3 to 5 weeks compared to the conventional tests.

  • TB susceptibility results in 7 days
  • Random access with 120 sample capacity
  • Incubation for TB culture
  • Fully automated optical imaging to monitor bacterial growth
  • Algorithm based image analysis technology
  • S/R results based on critical concentration
  • Automatic LIS transmission function

QuantaMatrix's microbial diagnostics solutions are the first to be developed in Korea and have received the highest honors including the New Excellent Technology (NET) certification and new medical technology certification.

TB drug susceptibility test results in a week

QDST provides results of drug susceptibility test for tuberculosis in just 7 days. Compared to conventional test methods, which takes 4 to 6 weeks, QDST dramatically reduces time to results.

* DST: Drug Susceptibility Test for Mycobacterium tuberculosis
QDST with liquid culture
  • Culture on liquid media
  • QDST
1 week DST
QDST with solid culture
  • Culture on solid media
  • QDST
1 week DST SAVE 5 WEEKS

Conventional solid culture DST
  • Culture on solid media
  • DST
6 week DST
0 1 2 3 4 5 6 7 8 9 10
weeks
  • 1 week

    Turn-around Time
    for TB DST

  • 3 Levels of Safety

    Protect Users

  • 120 Samples/Day

    with Random Access

QDST Kit

QDST Panel consists of 4 first line drugs and 9 second line drugs in 24 wells. Based on critical concentration, it is possible to provide susceptibility result for multidrug resistant (MDR) and extensively drug-resistant (XDR) tuberculosis.

First line Second line
Isoniazid Amikacin Ofloxacin
Rifampin Capreomycin Para-aminosalicylic acid
Rifabutin Kanamycin Streptomycin
Ethambutol Levofloxacin Ethionamide acid
Moxifloxacin

3-level safety

Since tuberculosis bacteria can be transmitted through the air, it is important for the user to conduct the test in a safe environment. QDST panel has a total of three levels of safety as shown below to prevent samples from leaking during the testing process.

  • Level 1

    Immobilizing tuberculosis bacteria in the agarose layer to suppress external leakage

  • Level 2

    Sealing with a panel sealer
    to prevent leakage of sample

  • Level 3

    Panel cover with safety lock

QDST Workflow

  • STEP 1

    Prepare mixture of cultured tuberculosis bacteria and agarose for immobilization.

  • STEP 2

    Dispense mixture and media on QDST panel containing preloaded, vacuum-dried antibiotics.

  • STEP 3

    Prepared panel is automatically loaded into 120 plate loaders in QDST.



  • STEP 4

    Observation of bacterial growth and resistance to the drug within 7days through fully automated optical imaging.

  • STEP 5

    Susceptibility results are reporting using proprietary algorithm and database based on critical concentration.

User-friendly interface

SIMPLE
Simple procedure Touchscreen with intuitive user interface
LIS
Bi-directional LIS connectivity Compatible with all major LIS
EFFICIENCY
Minimal hands-on time S/R results based on critical concentration